KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREBBP
All Species:
42.12
Human Site:
Y1519
Identified Species:
77.22
UniProt:
Q92793
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92793
NP_001073315.1
2442
265351
Y1519
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Chimpanzee
Pan troglodytes
XP_523285
2442
265358
Y1519
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095225
2442
265320
Y1519
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Dog
Lupus familis
XP_851777
2404
260682
Y1484
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
Y1520
A
E
R
I
I
N
D
Y
K
D
I
F
K
Q
A
Rat
Rattus norvegicus
NP_596872
2444
265618
Y1520
A
E
R
I
I
N
D
Y
K
D
I
F
K
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414964
2447
266615
Y1518
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Frog
Xenopus laevis
NP_001088637
2428
264402
Y1510
A
E
R
I
I
H
D
Y
K
D
I
F
K
Q
A
Zebra Danio
Brachydanio rerio
NP_001082924
2111
234059
A1328
R
D
A
F
L
T
L
A
R
D
K
H
W
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
Y2140
I
E
R
I
I
Q
D
Y
K
D
I
L
K
Q
A
Honey Bee
Apis mellifera
XP_001122031
2606
284119
Y1719
V
E
R
I
V
L
D
Y
K
D
I
L
K
Q
A
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
Y1273
P
P
S
E
G
D
D
Y
I
F
H
C
H
P
P
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
Y1727
G
D
G
V
I
N
I
Y
N
D
I
M
N
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.4
93.9
N.A.
94.8
95.8
N.A.
N.A.
88
76
61.5
N.A.
36.5
42.7
30.5
38.5
Protein Similarity:
100
99.9
99.6
95.5
N.A.
96.4
97.2
N.A.
N.A.
92
83.3
68.8
N.A.
46.7
54.7
43.9
50.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
100
6.6
N.A.
80
73.3
13.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
33.3
N.A.
80
80
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
0
8
0
0
0
0
8
0
0
0
0
0
8
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
16
0
0
0
8
85
0
0
93
0
0
0
0
0
% D
% Glu:
0
77
0
8
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
62
0
0
8
% F
% Gly:
8
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
47
0
0
0
0
8
8
8
0
0
% H
% Ile:
8
0
0
77
77
0
8
0
8
0
85
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
77
0
8
0
77
0
0
% K
% Leu:
0
0
0
0
8
8
8
0
0
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
24
0
0
8
0
0
0
8
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
77
0
% Q
% Arg:
8
0
77
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _